Hypertension is the most common modifiable risk factor for cardiovascular disease and death, and lowering blood pressure with antihypertensive drugs reduces target organ damage and prevents cardiovascular disease outcomes.

Most hypertensive patients will need a combination of antihypertensive agents to achieve the therapeutic goals. Recent guidelines recommend initiating treatment with two drugs in those patients with a systolic blood pressure >20 mmHg and/or a diastolic blood pressure >10 mmHg above the goals, and in those patients with high cardiovascular risk. In addition, approximately 25% of patients will require three antihypertensive agents to achieve the therapeutic targets.


APSC Consensus on Optimising CV Outcomes in T2D


19 April 2021


European Cardiology Review 2021;16:e14.

Importance of Aortic Dimensions in Determining Pulse Pressure in Elderly Hypertensives


Asia-Pacific Cardiology 2008;2(1):35-7

Why it is Important to Measure Blood Pressure at Home Rather than Just at the Clinic?


Asia-Pacific Cardiology 2011;3(1):41-4

Controlling Blood Pressure without Drugs - Developing New Strategies


Asia-Pacific Cardiology 2011;3(1):37–40